An effective treatment for baldness has been developed
There is hope for bald people. Korean scientists say they have succeeded in developing an effective drug that not only stops baldness, but also makes hair follicles begin to regenerate.
Researchers at Yonsei University in South Korea have developed a biochemical substance that ra can treat hair loss. The preparation stimulates the growth of flats in hair and prevents hair loss .
syndrome A research study led by Professor Choi Kang-yeol discovered that those who ers suffering from androgenetic alopecia have a significant amount of a protein called CXXC5. Androgenetic alopecia is the most common form of the disease. Affects 90 percent of men between the ages of 20 and 40. Causes the appearance of hair bends and, over time, hair thinning in the top of the head. But androgenetic alopecia also affects women causing uniform hair thinning all over the head.
Identified by Korean protein, CXXC5 acts as a negative regulator of the signaling pathway inside the com rki, which ra is associated with the development of flats in hair follicles and wound healing. Causes interruption of development and regeneration of hair follicles. Specific lnie, when it combines with another protein from the Dishevelled family.
Based on his research, who The results of which have been published in „Journal of Investigative Dermatology”, Researchers have developed a formulation called PTD-DBM, which ry prevents CXXC5 from binding to the dishevelled protein. The new substance may help c properly grow a hair follicle and regenerate an existing one.
PTD-DBM has been tested on rodents. For 28 days, the substance was applied to lab mice on the hairless part of the skin ry. After that, an increase in new dwellings was observed in hair. The researchers achieved the best results by combining the new substance with valproic acid, then the hair grew faster.
Existing treatments for alopecia will not work in humans, kt ers who had already lost their hair. Current preparations on the market only accelerate the rate of hair growth. But the new PTD-DBM formulation has the potential to achieve good results in this field as well.
Currently, the combined ł conducts experiments on animals to find out whether the new substance is not toxic and will not have the effect of in the side. But it will still have to wait for the results of the test before the formulation can be put on the market in clinical.
– We identified a protein that re controls hair growth. Based on this discovery, we developed a preparation that ry controls the function of the protein and leads to regeneration and growth of the dwelling in the hair. We expect that the newly developed substance will contribute to the creation of a drug that ry not only treats hair loss, but also regenerates damaged tissues sk ry – said Professor Choi Kang-yeol.